Antimutagenic Effect of Extract of Eleutherococcus senticosus Maxim

摘要: Antimutagenic effect of Eleutherococcus senticosus Maxim. on the mutagenicity induced by 2-AF and Trp-P-1 was studied using Ames test with Salmonella typhimurium TA98 TA100. In S. TA98, methanol extract root, stem, leaf E. showed inhibitory effects 72.8, 70.0, 78.7% 2-AF, 69.2, 64.9, 59.4% Trp-P-1, respectively, whereas none observed in These results suggest that inhibits a frame shift mutation. And then further fractionated chloroform, butanol, water. The chloroform fractions strong antimutagenic butanol aqueous fractions. dose-dependent manner.