Complications neurologiques centrales des traitements anticancéreux, ce que le réanimateur doit savoir

摘要: Cerebral radiation therapy and chemotherapies can trigger central nervous system complications. For some products protocols, neurological toxicity is a dose-limiting parameter. Clinical characteristics including acute encephalopathy, epilepsy, posterior reversible progressive multifocal leukoencephalopathy, vascular events are well described. Numerous involved in these complications most have specific profile. As more complex regimens used, several cytotoxic drugs innovative targeted therapies, new profiles emerging. The determination of the drug precisely patients’ symptoms getting difficult. A good knowing implicated agents helps managing oncologic reanimation care. Oncological prognostic has to be considered therapeutic discussion.