作者: Catherine Meignant
DOI:
关键词: Homogeneous 、 Vaginal dryness 、 Bioadhesive 、 Internal phase 、 Chromatography 、 Aqueous solution 、 Suspension (chemistry) 、 Materials science
摘要: This galenical form in intended to a local treatment, essentially non systemic, of the vaginal dryness, particularly menopaused women. It comprises free natural oestrogen, micronized or vectorized, selected amongst 17β-estradiol and its salts solution suspension lipophilic agent, with an oestrogen contents corresponding unit dose equivalent 15 νg at most, preferably less than 10 17β estradiol, bioadhesive gelifying hydrophilic agent hydrodispersible agent. on one hand, soft capsule, external solid hard envelope containing gelatine glycerin and, other liquid semi-liquid internal phase suspension, bioadhesion In sustained release ovule form, it semi-soft aqueous homogeneous