Her2 peptide regents and methods

作者: Thomas D. Wang , Bishnu P. Joshi

DOI:

关键词: Cancer researchDysplasiaCancer cellPeptideCancerEarly cancerMedicine

摘要: The present disclosure is directed to HER2-specific peptide reagents, methods for detecting pre-cancer (dysplasia), early cancer and/or using the and targeting pre-cancerous (dysplastic) cells, cells reagents.

参考文章(13)
David N. Krag, Stephanie C. Pero, Lyn Oligino, Binding peptides specific for the extracellular domain of erbb2 and uses therefor ,(2002)
Lingling Geng, Zihua Wang, Xiaoliang Yang, Dan Li, Wenxi Lian, Zhichu Xiang, Weizhi Wang, Xiangli Bu, Wenjia Lai, Zhiyuan Hu, Qiaojun Fang, Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors. Theranostics. ,vol. 5, pp. 1154- 1165 ,(2015) , 10.7150/THNO.12398
L. G. Trabuco, S. Lise, E. Petsalaki, R. B. Russell, PepSite: prediction of peptide-binding sites from protein surfaces Nucleic Acids Research. ,vol. 40, pp. 423- 427 ,(2012) , 10.1093/NAR/GKS398
José Baselga, Sandra M. Swain, Novel anticancer targets: revisiting ERBB2 and discovering ERBB3 Nature Reviews Cancer. ,vol. 9, pp. 463- 475 ,(2009) , 10.1038/NRC2656
Renata Pasqualini, Erkki Ruoslahti, Organ targeting In vivo using phage display peptide libraries Nature. ,vol. 380, pp. 364- 366 ,(1996) , 10.1038/380364A0
An Na Seo, Yoonjin Kwak, Duck-Woo Kim, Sung-Bum Kang, Gheeyoung Choe, Woo Ho Kim, Hye Seung Lee, HER2 Status in Colorectal Cancer: Its Clinical Significance and the Relationship between HER2 Gene Amplification and Expression PLoS ONE. ,vol. 9, pp. e98528- ,(2014) , 10.1371/JOURNAL.PONE.0098528
Lorenzo Fornaro, Maurizio Lucchesi, Chiara Caparello, Enrico Vasile, Sara Caponi, Laura Ginocchi, Gianluca Masi, Alfredo Falcone, Anti-HER agents in gastric cancer: from bench to bedside Nature Reviews Gastroenterology & Hepatology. ,vol. 8, pp. 369- 383 ,(2011) , 10.1038/NRGASTRO.2011.81
Kimberly Kelly, Herlen Alencar, Martin Funovics, Umar Mahmood, Ralph Weissleder, Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Research. ,vol. 64, pp. 6247- 6251 ,(2004) , 10.1158/0008-5472.CAN-04-0817
Paul W. Brandt-Rauf, Matthew R. Pincus, Walter P. Carney, The c- erbB -2 Protein in Oncogenesis: Molecular Structure to Molecular Epidemiology Critical Reviews in Oncogenesis. ,vol. 5, pp. 313- 329 ,(1994) , 10.1615/CRITREVONCOG.V5.I2-3.100
S. E. Cwirla, E. A. Peters, R. W. Barrett, W. J. Dower, Peptides on phage: a vast library of peptides for identifying ligands. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 6378- 6382 ,(1990) , 10.1073/PNAS.87.16.6378