作者: Paula T. Hammond , Amanda C. Engler , Hyung-Il Lee
DOI:
关键词: Yield (chemistry) 、 Ring-opening polymerization 、 Propargyl 、 L glutamate 、 Highly selective 、 Azide 、 Polymer chemistry 、 Alkyne 、 Click chemistry 、 Chemistry
摘要: A process of the present invention is directed toward conducting highly selective, high yield post-polymerization reactions on polypeptides to prepare functionalized polypeptides. In certain embodiments, can be prepared by ring opening polymerization N-carboxyanhydrides. reaction a "click chemistry" reaction. triazole-forming involving an alkyne polypeptide and azide.