Poly(propargyl-L-glutamate) and derivatives thereof

作者: Paula T. Hammond , Amanda C. Engler , Hyung-Il Lee

DOI:

关键词: Yield (chemistry)Ring-opening polymerizationPropargylL glutamateHighly selectiveAzidePolymer chemistryAlkyneClick chemistryChemistry

摘要: A process of the present invention is directed toward conducting highly selective, high yield post-polymerization reactions on polypeptides to prepare functionalized polypeptides. In certain embodiments, can be prepared by ring opening polymerization N-carboxyanhydrides. reaction a "click chemistry" reaction. triazole-forming involving an alkyne polypeptide and azide.

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