Sixty second-look procedures indicated primarily by rise in serial carcinoembryonic antigen.

摘要: Abstract Recurrent tumor was present at second-look operations in 56 of 60 patients (93.3%) reoperated upon during the past 7 years solely because serial carcinoembryonic antigen (CEA) values rose. later identified three remaining four patients; fourth had severe liver disease and undergoing hepatotoxic chemotherapy. Twenty-two were evaluated retrospectively; 38 entered a protocol are termed prospective (60.5%). Delay between rise CEA reoperation retrospective with unresectable months, contrast to 3.5 months those resectable tumor; while delay 4.5 only 1.5 months. Groups similar according Dukes' classification: B-7, C-14, D-1 (retrospective); B-10, C-26, D-2 (prospective). Serial determinations every 6 weeks for first 24 detected recurrent 93.3% patients. Incidence tumors increased when shortened. Twenty-one (35%) remain disease-free, longest time more than years. One additional negative patient is apparently free tumor. No operative death has occurred, major morbidity remains low (