Experimental Acute Renal Failure

摘要: Acute renal failure (ARF) has been studied in the laboratory for many years an attempt to define its pathophysiologic mechanisms and possible therapies either prevent, reverse, or ameliorate process. Like clinical counterpart, experimental ARF is characterized by considerable heterogeneity model variation as well a number of unifying characteristics. This chapter will review relevant systems describe current thoughts on vascular tubular cell injury with particular view highlighting clinically observations. Many agents have described which moderate setting, but few so far moved into practical usage it commonly observed that outcomes improved little recent decades. Nevertheless, observations from literature suggest promising avenues trials, these be reviewed final section.