作者: José A. Guijarro , Desirée Cascales , Ana I. García-Torrico , Mario García-Domínguez , Jessica Méndez
关键词: Virulence 、 Genetics 、 Gene 、 Biology 、 Bacteria 、 Transcription (biology) 、 Regulation of gene expression 、 Microbiology 、 Pathogenic bacteria 、 Gene expression 、 Ectotherm
摘要: Virulence gene expression in pathogenic bacteria is modulated by environmental parameters. A key factor this temperature. Its effect on virulence infecting warm-blooded hosts well documented. Transcription of genes these induced upon a shift from low to higher host temperature (37 oC). Interestingly, temperatures usually correspond the optimum for growth bacteria. On contrary, ectothermic such as fish, molluscs and amphibians, infection processes generally occur at lower than that optimal Therefore, regulation response has be different way which found hosts. The current understanding its fish-pathogenic limited, but constant extension our knowledge base essential enable rational approach problem bacterial fish diseases affecting aquaculture industry. This an interesting issue progress needs made order diminish economic losses caused diseases. intention review is, first time, compile scattered results existing field lay groundwork future research. article overview those relevant are expressed principal mechanisms could involved their regulation.