Prediction of the development of IgE-mediated atopic disorders and environmental engineering for their control.

摘要: Studies in recent years have demonstrated that many high-risk babies who develop atopic disease later life can be identified at birth by obtaining a positive family history and two laboratory tests on cord blood—serum IgE level number of suppressor T cells. The predictive value these has not been calculated precisely. sensitivity serum concentration is moderately high (~82%) the specificity evenhigher (~90%). However, cannot predict severity disease. Thus, test does differentiate between will only mild rhinitis those severe incapacitating bronchial asthma. development overcome shortcomings would desirable. Although underlying mechanisms allergic are poorly understood, preventive measures initiated infants with genetically or immunologically determined propensity to become sensitized beneficial. These include exclusive breast feeding, delayed introduction solids, reduced exposure animals dust, elimination tobacco smoke.