作者: Imad Al Kassaa , Didier Hober , Monzer Hamze , Delphine Caloone , Anny Dewilde
DOI: 10.1007/S00203-015-1101-8
关键词: Coxsackievirus 、 Viral envelope 、 Cytopathic effect 、 Lactobacillus gasseri 、 Virology 、 Biology 、 Virus 、 Viral Plaque Assay 、 Microbiology 、 Lactobacillus 、 Vero cell 、 Genetics 、 Biochemistry 、 Molecular biology 、 General Medicine
摘要: This study aimed at demonstrating the antiviral activity of Lactobacillus gasseri CMUL57 (L. CMUL57), L. acidophilus CMUL67 and plantarum CMUL140 against herpes simplex type 2 (HSV-2) Coxsackievirus B4E2 (CVB4E2), which are enveloped naked viruses, respectively. These lactobacilli were non-cytotoxic able to reduce cytopathic effect induced by HSV-2 in Vero cell monolayers. However, not active CVB4E2. Tested displayed anti-HSV-2 when they co-incubated with virus prior inoculating mixture The detection DNA PCR pellets bacteria/virus mixtures let us hypothesize that resulted from viruses' entrapment. showed capabilities vaginal inhibit viruses such as HSV-2.