The impact of lymphovascular invasion on survival in oral carcinoma

摘要: Summary Data was retrospectively analysed on 72 consecutive patients treated primarily with resection and concomitant neck dissection for intraoral carcinomas. Twenty prognostic variables were assessed by univariate analysis to assess their influence survival. Seven significant at the 5% level. Survival negatively influenced six tumour related factors, increasing T stage ( P  = 0.039), N  = 0.004), greater than two nodes histologically positive nodal disease  = 0.017), size >4 cm  = 0.022), residual primary site  = 0.012), extracapsular spread  = 0.01) one treatment factor analysed, adjuvant radiotherapy  = 0.039). Subsequent multivariate performed via cox stepwise regression method survival of all factors which achieved significance 20% There only made a difference  = 0.015) histological evidence mandibular invasion  = 0.047). Lymphovascular appeared in final model despite not achieving statistical level analysis. A constructed. The relative risk death those cervical metastases (N2 above) diagnosis 3.74  = 0.005). addition lymphovascular revealed an increase presence 2.99  = 0.015). Patients negative single node provided baseline as there no between these groups. oral carcinoma surgical specimens has impact outcome patients.