Treatment of COPD: the simplicity is a resolved complexity.
作者： Marco Candela , Rosario Costorella , Annalisa Stassaldi , Vanessa Maestrini , Giacomo Curradi
DOI: 10.1186/S40248-019-0181-8
关键词: Vital capacity 、 Simplicity 、 Disease 、 Medicine 、 Therapeutic algorithm 、 Intensive care medicine 、 FEV1/FVC ratio 、 COPD 、 Pulmonary disease
摘要: The introduction of simple and reproducible functional parameters as Forced Expiratory Volume in 1 s (FEV1) Vital Capacity (FVC) has been fundamental to diagnose, classify measure the progression Chronic Obstructive Pulmonary Disease (COPD). However, it recently emphasized that these do not allow an overview complexity heterogeneity COPD. In fact, disease can show several intrapulmonary extrapulmonary components with non-linear dynamic interactions which all are present patients nor individual patients, at time points [1]. These differences have justified recognition different phenotypes among objective this review is overhaul evidences published order define COPD characteristics able suggest a therapeutic algorithm.
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