Tumor heterogeneity makes AML a “moving target” for detection of residual disease

作者: W. Zeijlemaker , J. W. Gratama , G. J. Schuurhuis

DOI: 10.1002/CYTO.B.21134

关键词: DiseaseMinimal residual diseaseResidualCancer researchClone (B-cell biology)ImmunophenotypingImmunologyMyeloid leukemiaRisk factorBiologySomatic evolution in cancer

摘要: … minimal residual disease markers. In this review the role of such changes in minimal residual disease … Although the actual mechanisms by which phenotype changes occur are unclear, …

参考文章(95)
Eric L Sievers, Beverly J Lange, Todd A Alonzo, Robert B Gerbing, Irwin D Bernstein, Franklin O Smith, Robert J Arceci, William G Woods, Michael R Loken, Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia. Blood. ,vol. 101, pp. 3398- 3406 ,(2003) , 10.1182/BLOOD-2002-10-3064
Jesús F. San Miguel, Marı́a B. Vidriales, Consuelo López-Berges, Joaquı́n Dı́az-Mediavilla, Norma Gutiérrez, Consuelo Cañizo, Fernando Ramos, Marı́a J. Calmuntia, José J. Pérez, Marcos González, Alberto Orfao, Early immunophenotypical evaluation of minimal residual disease in acute myeloid leukemia identifies different patient risk groups and may contribute to postinduction treatment stratification. Blood. ,vol. 98, pp. 1746- 1751 ,(2001) , 10.1182/BLOOD.V98.6.1746
J. Nomdedeu, E. Bussaglia, N. Villamor, C. Martinez, J. Esteve, M. Tormo, C. Estivill, M.P. Queipo, R. Guardia, M. Carricondo, M. Hoyos, A. Llorente, J. Juncà, M. Gallart, A. Domingo, J. Bargay, M. Mascaró, J.M. Moraleda, L. Florensa, J.M. Ribera, D. Gallardo, S. Brunet, A. Aventin, J. Sierra, Immunophenotype of acute myeloid leukemia with NPM mutations: prognostic impact of the leukemic compartment size. Leukemia Research. ,vol. 35, pp. 163- 168 ,(2011) , 10.1016/J.LEUKRES.2010.05.015
Tatsuya Suzuki, Hitoshi Kiyoi, Kazutaka Ozeki, Akihiro Tomita, Satomi Yamaji, Ritsuro Suzuki, Yoshihisa Kodera, Shuichi Miyawaki, Norio Asou, Kazutaka Kuriyama, Fumiharu Yagasaki, Chihiro Shimazaki, Hideki Akiyama, Miki Nishimura, Toshiko Motoji, Katsuji Shinagawa, Akihiro Takeshita, Ryuzo Ueda, Tomohiro Kinoshita, Nobuhiko Emi, Tomoki Naoe, Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia Blood. ,vol. 106, pp. 2854- 2861 ,(2005) , 10.1182/BLOOD-2005-04-1733
Nikolay D. Dimov, L. Jeffrey Medeiros, Farhad Ravandi, Carlos E. Bueso-Ramos, Acute Promyelocytic Leukemia at Time of Relapse Commonly Demonstrates Cytogenetic Evidence of Clonal Evolution and Variability in Blast Immunophenotypic Features American Journal of Clinical Pathology. ,vol. 133, pp. 484- 490 ,(2010) , 10.1309/AJCPJ7K0AWMBHMAI
David Grimwade, Robert K. Hills, Anthony V. Moorman, Helen Walker, Stephen Chatters, Anthony H. Goldstone, Keith Wheatley, Christine J. Harrison, Alan K. Burnett, , Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials Blood. ,vol. 116, pp. 354- 365 ,(2010) , 10.1182/BLOOD-2009-11-254441
Iris H. I. M. Hollink, Marry M. van den Heuvel-Eibrink, Martin Zimmermann, Brian V. Balgobind, Susan T. C. J. M. Arentsen-Peters, Marielle Alders, Andre Willasch, Gertjan J. L. Kaspers, Jan Trka, Andre Baruchel, Siebold S. N. de Graaf, Ursula Creutzig, Rob Pieters, Dirk Reinhardt, C. Michel Zwaan, Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia. Blood. ,vol. 113, pp. 5951- 5960 ,(2009) , 10.1182/BLOOD-2008-09-177949
Susanne Schnittger, Claudia Schoch, Martin Dugas, Wolfgang Kern, Peter Staib, Christian Wuchter, Helmut Löffler, Cristina Maria Sauerland, Hubert Serve, Thomas Büchner, Torsten Haferlach, Wolfgang Hiddemann, Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood. ,vol. 100, pp. 59- 66 ,(2002) , 10.1182/BLOOD.V100.1.59
Danielle Sainty, Béatrice Gaugler, Daniel Olive, Régis T. Costello, Jean-Albert Gastaut, Françoise Mallet, Christine Arnoulet, Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities. Cancer Research. ,vol. 60, pp. 4403- 4411 ,(2000)
Daniela Hoehn, L. Jeffrey Medeiros, Su S. Chen, Tian Tian, Jeffrey L. Jorgensen, Yasin Ahmed, Pei Lin, CD117 Expression Is a Sensitive but Nonspecific Predictor of FLT3 Mutation in T Acute Lymphoblastic Leukemia and T/Myeloid Acute Leukemia American Journal of Clinical Pathology. ,vol. 137, pp. 213- 219 ,(2012) , 10.1309/AJCPR3N3JMSYLPFG