Risk factors for multi-drug resistant tuberculosis in patients at tertiary care hospital, Peshawar.

摘要: Objective To determine the frequency of common risk factors for multi-drug resistant tuberculosis in patients presented at a tertiary care hospital, Peshawar. Study design Cross-sectional, observational study. Place and duration study Pulmonology Department, Khyber Teaching Hospital, Peshawar, from December 2006 to October 2007. Methodology Patients with positive AFB culture sensitivity results found both rifampicin isoniazid or resistance other first line anti-tuberculosis drugs, were recruited Ward Outpatient Department (OPD). Informed verbal consent was taken questionnaire administered all participants Information regarding demographics, education status, occupation, monthly household income, C/S, details past history family TB Multi-Drug Resistant (MDR-TB) recorded. Data analyzed on SPSS version 11. Results A total 30 MDR-TB interviewed. Male (n=17) female (n=13) ratio 1.3:1. Mean age 34.2+/-15.3 years. Ninety-two percent 52.9% male uneducated. In 56.7%, income less than 5,000 rupees 40% between 5,000-10,000 rupees. All had previous Antituberculous Treatment (ATT), which 20% undertaken ATT course once, 53.3% twice 26.7% thrice past. group, 13 (43.3%) not completed their 11 them receiving general practitioner (GP) that time. Seven (23.3%) but no one documented family. Resistance RH present patients; moreover, 56.7% RHEZ+S. Conclusion The most group tuberculosis, repeated courses ATT, prescribed by different clinicians unsupervised treatment GP during initial ATT.