作者: Barbara G. Isaac , Stephen W. Ayer , Richard J. Stonard
DOI: 10.1007/978-1-4615-3012-1_11
关键词: Microorganism 、 Microbial metabolite 、 Structural diversity 、 Metabolite 、 Biotechnology 、 Biology 、 Chemical screening
摘要: The success of any high throughput chemical screening program is largely dependent upon the quality and structural diversity compounds tested. exceptional biosynthetic capabilities microorganisms suggest that search for novel microbial metabolites possessing activity against plant diseases, insects, weeds could be a particularly valuable addition to classical synthetic screen.1 This approach has been validated by commercial introduction weed control products based streptomycete metabolite phosphinothricylalanylalanine2 insect avermectin.3