Microorganisms: A Remarkable Source of Diverse Chemical Structures for Herbicide Discovery

作者: Barbara G. Isaac , Stephen W. Ayer , Richard J. Stonard

DOI: 10.1007/978-1-4615-3012-1_11

关键词: MicroorganismMicrobial metaboliteStructural diversityMetaboliteBiotechnologyBiologyChemical screening

摘要: The success of any high throughput chemical screening program is largely dependent upon the quality and structural diversity compounds tested. exceptional biosynthetic capabilities microorganisms suggest that search for novel microbial metabolites possessing activity against plant diseases, insects, weeds could be a particularly valuable addition to classical synthetic screen.1 This approach has been validated by commercial introduction weed control products based streptomycete metabolite phosphinothricylalanylalanine2 insect avermectin.3

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