Association of HLA Antigen A9 with Progressive Systemic Sclerosis (Scleroderma)
作者： Philip J. Clements , Gerhard Opelz , Paul I. Terasaki , M. Ray Mickey , Daniel Furst
DOI: 10.1111/J.1399-0039.1978.TB01268.X
关键词: Immunology 、 Epitope 、 Progressive systemic sclerosis 、 Diffuse scleroderma 、 Locus (genetics) 、 Histocompatibility Testing 、 Human leukocyte antigen 、 Medicine
摘要: Upon evaluation of 40 subjects with progressive systemic sclerosis (PSS), a significant association HLA antigens A9 and Aw24 (a subgroup A9) was found diffuse scleroderma. HLA-Aw23 second also increased in the patients, however, this not statistically significant. Diffuse scleroderma appears to be one few diseases that shows an HLA-A locus.
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