Profile of Scott J. Hultgren.

Anthony J. Schaeffer, Susan K. Amundsen, Lawrence N. Schmidt, Adherence of Escherichia coli to human urinary tract epithelial cells. Infection and Immunity. ,vol. 24, pp. 753- 759 ,(1979) , 10.1128/IAI.24.3.753-759.1979

Thomas J. Hannan, Indira U. Mysorekar, Chia S. Hung, Megan L. Isaacson-Schmid, Scott J. Hultgren, Early Severe Inflammatory Responses to Uropathogenic E. coli Predispose to Chronic and Recurrent Urinary Tract Infection PLOS Pathogens. ,vol. 6, ,(2010) , 10.1371/JOURNAL.PPAT.1001042

K. W. Dodson, F. Jacob-Dubuisson, R. T. Striker, S. J. Hultgren, Outer-membrane PapC molecular usher discriminately recognizes periplasmic chaperone-pilus subunit complexes. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 3670- 3674 ,(1993) , 10.1073/PNAS.90.8.3670

B. Lund, F. Lindberg, B. I. Marklund, S. Normark, The PapG protein is the alpha-D-galactopyranosyl-(1----4)-beta-D-galactopyranose-binding adhesin of uropathogenic Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 5898- 5902 ,(1987) , 10.1073/PNAS.84.16.5898

D. J. Schwartz, V. Kalas, J. S. Pinkner, S. L. Chen, C. N. Spaulding, K. W. Dodson, S. J. Hultgren, Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 110, pp. 15530- 15537 ,(2013) , 10.1073/PNAS.1315203110

Matthew A Mulvey, Yolanda S Lopez-Boado, Carole L Wilson, Robyn Roth, William C Parks, John Heuser, Scott J Hultgren, Induction and Evasion of Host Defenses by Type 1-Piliated Uropathogenic Escherichia coli Science. ,vol. 282, pp. 1494- 1497 ,(1998) , 10.1126/SCIENCE.282.5393.1494

Zhenfu Han, Jerome S. Pinkner, Bradley Ford, Robert Obermann, William Nolan, Scott A. Wildman, Doug Hobbs, Tom Ellenberger, Corinne K. Cusumano, Scott J. Hultgren, James W. Janetka, Structure-based drug design and optimization of mannoside bacterial FimH antagonists. Journal of Medicinal Chemistry. ,vol. 53, pp. 4779- 4792 ,(2010) , 10.1021/JM100438S

S. J. Hultgren, F. Lindberg, G. Magnusson, J. Kihlberg, J. M. Tennent, S. Normark, The PapG adhesin of uropathogenic Escherichia coli contains separate regions for receptor binding and for the incorporation into the pilus. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 86, pp. 4357- 4361 ,(1989) , 10.1073/PNAS.86.12.4357

B. A. Ford, J. R. Crowley, J. P. Henderson, J. W. Janetka, S. J. Hultgren, C. K. Cusumano, J. S. Pinkner, Z. Han, S. E. Greene, Treatment and Prevention of Urinary Tract Infection with Orally Active FimH Inhibitors Science Translational Medicine. ,vol. 3, ,(2011) , 10.1126/SCITRANSLMED.3003021

J. S. Pinkner, H. Remaut, F. Buelens, E. Miller, V. Aberg, N. Pemberton, M. Hedenstrom, A. Larsson, P. Seed, G. Waksman, S. J. Hultgren, F. Almqvist, Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 17897- 17902 ,(2006) , 10.1073/PNAS.0606795103