Microsatellites, from molecules to populations and back

作者: Philippe Jarne , Pierre J.L. Lagoda

DOI: 10.1016/0169-5347(96)10049-5

关键词: Null alleleMutation (genetic algorithm)Selection (genetic algorithm)PopulationPopulation geneticsMendelian inheritanceGeneticsBiologyGenetic structureMicrosatellite

摘要: Population genetics studies using microsatellites, and data on their molecular dynamics, are on the increase. But, so far, no consensus has emerged on which mutation model should be used, though this is of paramount importance for analysis of population genetic structure. However, this is not surprising given the variety of microsatellite molecular motifs. Null alleles may be disturbing for population studies, even though their presence can be detected through careful population analyses, while homoplasy seems of little concern, at …

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