Determining the predictive capability of a Clinical Assessment Scoring Chart to differentiate severity of the clinical consequences of neonatal calf diarrhea relative to gold-standard blood gas analysis.

摘要: Neonatal calf diarrhea (NCD) is a major problem to health worldwide, in terms of both morbidity and mortality. A five-point ordinal scale clinical assessment scoring (CAS) chart was utilized assess calves suffering from NCD-related abnormalities (acidosis dehydration) on commercial farms. The objective this research determine the predictive capability CAS against gold standard blood gas parameters, designed assist farmers accurate consequences NCD. total 443 diarrheic non-diarrheic were enrolled study. rated calf’s no signs varying degrees severity 0 (clinically normal) 4 (grave) scale, based indicators including demeanour, ear position, mobility, suckle reflex, desire-to-feed, enophthalmos. Blood analysis conducted for individual calves, consisting pH, base excess, Na+, K+, Ca2+, Cl−, glucose, hemoglobin, bicarbonate, anion gap, strong ion difference. Statistical evaluation performed by comparison score with profiles using logistic regression non-parametric estimation Receiver Operating Characteristics (ROC). ROC indicated that had acceptable specificity (>95%) low sensitivity ( 80%) but reduced accuracy differentiating mild moderate cases (peak estimations >50%). chart, as presented, provides simple tool differentiate clinically normal diarrhea, fails accurately NCD related acidosis dehydration. Further efforts are required enhance differential diagnostic value type chart.