Effect of Thoracic Displacement and Vagotomy on the Canine Gastroesophageal Junctional Zone

作者: James F. Lind , David J. Cotton , Robert Blanchard , John S. Crispin , George E. Dimopolos

DOI: 10.1016/S0016-5085(69)80010-7

关键词: StomachAbdomenParaesophagealRefluxMedicineVagus nerveEsophagusVagotomyAnatomyReflux esophagitis

摘要: This study was undertaken to delineate the functional importance of paraesophageal structures and vagal innervation in maintaining gastroesophageal competence. Intraluminal pressures were recorded from canine stomach, esophagus, junctional zone, before after surgical displacement zone into thorax; vagotomy at level junction; replacement within abdomen. The results suggest that anatomical position and, therefore, structures, do not contribute high pressure are important Division vagus nerves junction resulted a decrease resting sphincteric response abdominal compression, allowing free reflux occur. Afferent impulses arising below diaphragm exert controlling influence on integrity sphincter. Vagotomy creates model incompetence proposed for experimental esophagitis.

参考文章(19)
Charles F. Code, An Atlas Of Esophageal Motility In Health And Disease Dr. Robert Heiling Library, S.m.s.medical College, Jaipur. ,(1958)
Richard Nagler, Howard M. Spiro, Segmental Response of the Inferior Esophageal Sphincter to Elevated Intragastric Pressure Gastroenterology. ,vol. 40, pp. 405- 407 ,(1961) , 10.1016/S0016-5085(61)80073-5
J. F. Lind, J. S. Crispin, D. K. McIver, The effect of atropine on the gastroesophageal sphincter. Canadian Journal of Physiology and Pharmacology. ,vol. 46, pp. 233- 238 ,(1968) , 10.1139/Y68-039
Werner Zeller, G. E. Burget, A study of the cardia Digestive Diseases and Sciences. ,vol. 4, pp. 113- 120 ,(1937) , 10.1007/BF03010342
CHEVALIER JACKSON, The diaphragmatic pinchcock in so‐called “cardiospasm” Laryngoscope. ,vol. 32, pp. 139- 142 ,(1922) , 10.1288/00005537-192202000-00010
Earl Fyke, Jr., Charles F. Code, Jerry F. Schlegel, The gastroesophageal sphincter in healthy human beings. Digestion. ,vol. 86, pp. 135- 150 ,(1956) , 10.1159/000200544
Jerry F. Schlegel, Charles F. Code, Pressure characteristics of the esophagus and its sphincters in dogs. American Journal of Physiology. ,vol. 193, pp. 9- 14 ,(1958) , 10.1152/AJPLEGACY.1958.193.1.9
Richard K. Greenwood, Jerry F. Schlegel, Walter J. Helm, Charles F. Code, Pressure and Potential Difference Characteristics of Surgically Created Canine Hiatal Hernia Gastroenterology. ,vol. 48, pp. 602- 611 ,(1965) , 10.1016/S0016-5085(65)80038-5
McIver Dk, Lind Jf, Crispin Js, Manometric study of the effect of vagotomy on the gastroesophageal sphincter. Canadian Journal of Surgery. ,vol. 10, pp. 299- 303 ,(1967)
Wankling Wj, Warrian Wg, Lind Jf, THE GASTROESOPHAGEAL SPHINCTER IN HIATUS HERNIA. Canadian Journal of Surgery. ,vol. 8, pp. 61- ,(1965)