Expression of thyroid transcription factor-1 and other markers in sclerosing hemangioma of the lung.
作者： Peter B. Illei , Juan Rosai , David S. Klimstra
DOI: 10.5858/2001-125-1335-EOTTFA
关键词: Lung 、 Hemangioma 、 Pulmonary Sclerosing Hemangioma 、 Thyroid Transcription Factor 1 、 Chromogranin A 、 Hemangioendothelioma 、 Thyroid 、 CD31 、 Pathology 、 Medicine
摘要: Abstract Context.—Sclerosing hemangioma of the lung is well characterized histologically, but line differentiation expressed by tumor cells has been unclear. Despite implication its name a vascular neoplasm, sclerosing considered most authorities to be an epithelial tumor, possibly related pulmonary epithelium. Objectives.—To determine with immunohistochemistry and review literature. Design.—Nine cases histologically typical were studied pan-epithelial (epithelial membrane antigen [EMA] CAM 5.2), endothelial (CD31), neuroendocrine (chromogranin A), markers (thyroid transcription factor-1 PE10). Staining intensity was separately evaluated in pale solid areas lining papillary structures. Results.—Both cell types positive for thyroid EMA all (100%). Thyroid...
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