Effects of Ethanol Intake on High Density Lipoprotein Metabolism in Humans

摘要: Moderate ethanol intake consistently has been associated with a decreased risk of cardiovascular disease (CVD) in observational studies [1-3], although the decrease is most pronounced and consistent for coronary heart [1] less so stroke [1]. Although few have shown increases [4] or no changes [5] carotid atherosclerosis by ultrasound (carotid intima-media thickness, CIMT) moderate intake, reported CIMT men but curiously change women [6-8]. Heavy appears to adverse effects on [9, 10]. Ethanol favorably affect many factors CVD, including antithrombotic/anticoagulant (see ref. [11] review) antiinflammatory [12] review). The best-studied effect, however, an increase plasma concentrations high density lipoprotein (HDL), it estimated that about half relationship between CVD may be attributed its HDL [3, 12]. For these reasons, metabolism, as outlined this chapter, are clinical, well research interest.