Cloning of the gene encoding human somatostatin receptor 2: Sequence analysis of the 5′-flanking promoter region

作者: Michael T. Greenwood , Lauri-Ann Robertson , Yogesh C. Patel

DOI: 10.1016/0378-1119(95)00059-F

关键词: Untranslated regionComplementary DNASequence analysisSomatostatin receptor 2GeneticsStart codonPromoterGeneMolecular biologySomatostatin receptorBiology

摘要: Abstract Using a cDNA probe, genomic clones were obtained for the 5′ flanking promoter sequence of human somatostatin receptor 2-encoding gene (SSTR2). A 3.8-kb directly upstream from start codon was analyzed. This shares number characteristics with promoters other G-protein-coupled (GPCR)-encoding genes including G + C-rich regions, binding sites several transcriptional factors, and absence coupled TATAA CAAT sequences.

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