The association of smoking with cardiomyopathy.

作者: Arthur J. Hartz , Alfred J. Anderson , Harold L. Brooks , Jack C. Manley , Gerard T. Parent

DOI: 10.1056/NEJM198411083111901

关键词: Myocardial diseaseCoronary angiographyMyocardial infarctionCardiomyopathyRelative riskMedicineCardiologyOdds ratioCoronary occlusionInternal medicineWall motion

摘要: Abstract We investigated the possibility that smoking has an association with ventricular wall-motion abnormalities is independent of its known coronary occlusion. studied 4763 men between ages 35 and 74 who had diagnostic angiography ventriculography. considered three kinds abnormalities: hypokinesis in one to four segments, five six segments (diffuse hypokinesis), akinetic or dyskinetic wall motion at least segment. Among younger than 55, relative risk diffuse was 2.78 (1.1 6.99) for heavy smokers as compared nonsmokers. Adjusting degree occlusion eliminating subjects a history myocardial infarction did not change this risk. were 55 older (odds ratio nonsmokers) significant (0.55 2.28). Regardless age akinesis dys...

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