Dating the endometrial biopsy.

摘要: It is asserted that examination of the endometrium during secretory phase yields more information about time ovulation degree progestational change and normality than any other test used in sterility studies. Attention to qualitative changes 8 morphological factors most useful dating endometrial biopsy. During 1st week luteal activity attention should be focused on occurring gland epithelium: mitosis pseudostratification nuclei basal vacuolation secretion. 2nd stromal (including edema) predecidual reaction leukocytic infiltration are key criteria. Tissue from fundus uterus gives reliable information. These critera were 300 biopsies taken normally menstruating women over a 3-year period. Absence organic disease availability accurate menstrual history only selection 12 observers dated biopsies. 42 patients (14%) menstruated day predicted 36 (12%) later 222 (74%) earlier. When +or- 1 error was allowed 112 (38%) found menstruate at predicted. these same slides reviewed by single observer date for advanced area biopsy 179 (60%) within prediction. To validity criteria body temperature correlate with rather onset menstruation. Of 40 who had adequate records 31 (78%) ovulated as allowing indicating better gauge duration progesterone effect predictor menses. determine whether caused early menstruation phases 25 recorded temperatures least 2 cycles addition which examined. The definitely shorter biopsied control cycle suggesting does accelerate flow. However further analysis showed not interfere length flow or succeeding rhythm.