Effects of Subthalamic Nucleus Deep Brain Stimulation on Facial Emotion Recognition in Parkinson's Disease: A Critical Literature Review.

摘要: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for Parkinson’s disease (PD). Nevertheless, DBS has been associated with certain nonmotor, neuropsychiatric effects such as worsening emotion recognition from facial expressions. In order to investigate (FER) after STN DBS, we conducted a literature search electronic databases MEDLINE and Web science. this review, analyze studies assessing FER in PD patients summarize current knowledge on FER. The majority studies, which had clinical methodological heterogeneity, showed that patients, particularly negative emotions (sadness, fear, anger, tendency disgust). can be attributed functional role limbic circuits interference neural networks involved FER, including connections part basal ganglia pre- frontal areas. These outcomes improve our understanding integration motor, cognitive, emotional aspects behaviour growing field affective neuroscience. Further using standardized neuropsychological measures assessment larger cohorts are needed, draw definite conclusions about effect its impact patients’ quality life.