DNA-to-protein crosslinks and backbone breaks caused by far- and near-ultraviolet, and visible light radiations in mammalian cells.

摘要: The cytotoxic, mutagenic and carcinogenic potential of germicidal far-UV* radiation has been known for decades. This is not a major component the solar radiations that reach surface earth, unlike abundant near-UV visible present in spectrum. Although it recognized decades mixture mid-UV, near-UV, (wavelengths longer than 290 nm) comprise sunlight mutagenic, carcinogenic,1 surprisingly little attention paid to specific DNA damages may be caused cells by these particular wavelengths nonionizing radiation—even though are environmentally abundant, penetrate deeply through skin, increasingly used cosmetic purposes (natural artificial exposure human skin).