Use of ACTH and Cortisone in the Treatment of Post-Irradiation Pulmonary Reaction

作者: Stuart W. Cosgriff , Morton M. Kligerman

DOI: 10.1148/57.4.536

关键词: LungInternal medicineHormoneSurgeryAdrenocorticotropic hormonePulmonary granulomatosisPulmonary fibrosisMedicineGastroenterologyRadiation therapyNodule (medicine)Cortisone

摘要: With the present trend toward higher radiation dosages in an attempt to control pulmonary, esophageal, and other thoracic lesions, danger of producing post-irradiation pulmonary fibrosis has increased. Adrenocorticotropic hormone (ACTH) been reported by Kennedy et al. (1) as beneficial effects a patient with beryllium granulomatosis. West his associates (2) have observed clinical improvement two patients who were treated ACTH cortisone. Because these results, cortisone recently employed whom unusually severe reaction lung occurred after roentgen therapy for metastasis. Inasmuch appeared not only halt but partially reverse acute phase reaction, it seemed worth while record this case. G. K., 68-year-old female, was referred May 1950, consideration radiotherapy solitary metastatic nodule right middle ...

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