Country planning for health interventions under development: lessons from the malaria vaccine decision-making framework and implications for other new interventions

摘要: Traditionally it has taken years or decades for new public health interventions targeting diseases found in developing countries to be accessible those most need. One reason the delay been insufficient anticipation of eventual processes and evidence required decision making by countries. This paper describes research into anticipated data needed inform on malaria vaccines, advanced which is still phase 3 trials. From 2006 2008, a series country consultations Africa led development guide assist preparing their vaccine decision-making frameworks. The builds upon World Health Organization’s Vaccine Introduction Guidelines. It identifies decisions, when they would relative timelines intervention, where will come from. Policy supported (e.g. disease burden; roles other interventions; impact; economic financial issues; efficacy, quality safety) as implementation decisions programmatic issues socio-cultural environment). generic can now applied any future vaccine. discusses opportunities challenges early planning decision-making—from potential timely, evidence-informed risks over-promising around an intervention under development. Careful well-structured important way ensure that do not remain unused after become available.