Visual Function in Alzheimer's Disease and Normal Aginga

作者: ALICE CRONIN-GOLOMB , JOSEPH F. RIZZO , SUZANNE CORKIN , JOHN H. GROWDON

DOI: 10.1111/J.1749-6632.1991.TB00186.X

关键词: Stereoscopic acuityRetinaAudiologyDiseaseBackward maskingOptic nerveVisual functionFlicker fusion thresholdContrast (vision)Medicine

摘要: We examined a wide range of visual behaviors in 59 patients with Alzheimer's disease (AD), 35 elderly control subjects, and 12 young subjects. A subset the AD received neuro-ophthalmologic electrophysiologic examinations order to evaluate integrity retino-calcarine pathway. Patients showed significant, selective losses function, including color discrimination, stereoacuity, contrast sensitivity, backward masking, but not critical flicker fusion. The deficits were attributable clinically apparent lesions retina or optic nerve. therefore suggest that primary posterior association cortices underlie observed behavioral abnormalities.

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