Dnt-maleate and methods of preparation thereof
作者： Mili Abramov , Anita Liberman , Santiago Ini , Tamas Koltai
DOI:
关键词: Organic chemistry 、 Pharmacology 、 Duloxetine Hydrochloride 、 Chemistry
摘要: (S)-N,N-Dimethyl-3-(l-naphtlialenyloxy)-3-(2-thienyl)propanamine nialeate (DNT-maleate) and polymorphs of DNT-maleate, compositions DNT-maleate its polymorphs, processes for the preparation duloxetine hydrochloride from are provided.
lens.org 参考文章(34)
Chava Satyanarayana, Chavakula Ramdas, Konudula Babu Rao, Gorantla Seeta Ramanjaneyulu, An improved process for the preparation of duloxetine ,(2006)
Gilbert Stanley Staten, Michael Alexander Staszak, Leland Otto Weigel, Chiral synthesis of 1-aryl-3-aminopropan-1-ols ,(1991)
Stephen Benedict David Winter, Improved synthesis and preparations of duloxetine salts ,(2006)
Petr Hruby, Miroslav Kuchar, Lukas Placek, Ludek Ridvan, Method of manufacturing (s)-n-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride (duloxetine) ,(2005)
Atsushi Yuzawa, Kenichi Sakai, Rumiko Sakurai, Kaoru Hatahira, Process for preparing optically active 3-(methylamino)-1-(2-thienyl) propan-1-ol and intermediates for preparation ,(2004)
Douglas Patton Kjell, Kurt Thomas Lorenz, Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof ,(2000)
Kenneth Moder, Alain Merschaert, Mark Butchko, Improved process for the asymmetric synthesis of duloxetine ,(2006)
TADASHI KOMETANI, SHUNSAKU SHIOTANI, KEMMOTSU MITSUHASHI, On the cleavage of tertiary amines with ethyl chloroformate. Chemical & Pharmaceutical Bulletin. ,vol. 24, pp. 342- 349 ,(1976) , 10.1248/CPB.24.342
Perea Juan Jose Almena, Michael Schwarm, Hans Peter Krimmer, Dietmar Reichert, Karlheinz Drauz, Preparation of n-methyl-3-hydroxy- 3-(2-thienyl)propylamine via novel thiophene derivatives containing carbamate groups as intermediates ,(2003)
Clarke Slemon, Process for the preparation of pure thiophene derivatives ,(1992)