Asymmetric Inheritance of Radial Glial Fibers by Cortical Neurons

作者: Takaki Miyata , Ayano Kawaguchi , Hideyuki Okano , Masaharu Ogawa

DOI: 10.1016/S0896-6273(01)00420-2

关键词: NeuroscienceRadial glial cellNeurogliaBiologyNeuriteCerebral cortexNeuronSomal translocationInterkinetic nuclear migrationCell division

摘要: Recent studies demonstrated the neuronogenic role of radial glial cells (RGCs) in rodent. To reveal fate processes, we intensively monitored divisions RGCs DiI-labeled slices from embryonic day 14 mouse cortex. During RGC division, each pia-connected fiber becomes thin but is neither lost nor divided; it inherited asymmetrically by one daughter cell. In that produce a neuron and progenitor, inherits pial fiber, also grows thick ventricular process for several hours, therefore indistinguishable progenitor RGC. The glial-like ("radial neuron") then collapses, leading to ascent using "recycled" fiber.

参考文章(55)
Y. Kaneko, S. Sakakibara, T. Imai, A. Suzuki, Y. Nakamura, K. Sawamoto, Y. Ogawa, Y. Toyama, T. Miyata, H. Okano, Musashi1: An evolutionally conserved marker for CNS progenitor cells including neural stem cells Developmental Neuroscience. ,vol. 22, pp. 139- 153 ,(2000) , 10.1159/000017435
S. McConnell, C. Kaznowski, Cell cycle dependence of laminar determination in developing neocortex Science. ,vol. 254, pp. 282- 285 ,(1991) , 10.1126/SCIENCE.1925583
Perry A. Brittis, Karina Meiri, Erik Dent, Jerry Silver, The Earliest Patterns of Neuronal Differentiation and Migration in the Mammalian Central Nervous System Experimental Neurology. ,vol. 134, pp. 1- 12 ,(1995) , 10.1006/EXNR.1995.1031
Jean-Paul Misson, Michael A. Edwards, Miyuki Yamamoto, Verne S. Caviness, Identification of radial glial cells within the developing murine central nervous system:studies based upon a new immunohistochemical marker Developmental Brain Research. ,vol. 44, pp. 95- 108 ,(1988) , 10.1016/0165-3806(88)90121-6
M. BERRY, A. W. ROGERS, J. T. EAYRS, PATTERN OF CELL MIGRATION DURING CORTICAL HISTOGENESIS. Nature. ,vol. 203, pp. 591- 593 ,(1964) , 10.1038/203591B0
J. Lo Turco, A. Kriegstein, Clusters of coupled neuroblasts in embryonic neocortex. Science. ,vol. 252, pp. 563- 566 ,(1991) , 10.1126/SCIENCE.1850552
N. O'Rourke, M. Dailey, S. Smith, S. McConnell, Diverse migratory pathways in the developing cerebral cortex. Science. ,vol. 258, pp. 299- 302 ,(1992) , 10.1126/SCIENCE.1411527
R. M. Seymour, M. Berry, Scanning and transmission electron microscope studies of interkinetic nuclear migration in the cerebral vesicles of the rat. The Journal of Comparative Neurology. ,vol. 160, pp. 105- 125 ,(1975) , 10.1002/CNE.901600107
Jean-Paul Misson, Takao Takahashi, Verne S. Caviness, Ontogeny of radial and other astroglial cells in murine cerebral cortex. Glia. ,vol. 4, pp. 138- 148 ,(1991) , 10.1002/GLIA.440040205