Sero-prevalence of latent Toxoplasma gondii infection among HIV-infected and HIV-uninfected people in Addis Ababa, Ethiopia: A comparative cross-sectional study

摘要: Toxoplasmosis in immuno-compromised hosts manifests primarily as a life threatening condition, toxoplasmic encephalitis. However, there is scarce information about the magnitude of Toxoplasma gondii infection among HIV-infected people Ethiopia. This study was, therefore, conducted to determine sero-prevalence T. and HIV-uninfected subjects. Sera were collected from with without HIV for purpose studying hepatitis B virus (HBV) at St. Paul Hospital, Addis Ababa, Ethiopia 24 January 2007 15 February 2007. Among these sera, first 330 consecutive 165 each sero-group, selected tested anti-T. IgG antibodies using Enzyme Linked Immunosorbent Assay. The seroprevalence was assessed against socio-demographic characteristics, HBV serostatus HBV-related risk factors. overall latent subjects 90.0%. observed respective prevalence 93.3% 86.7% people. Though seems be influenced by age, gender serostatus, only significantly associated (OR 2.71, CI 1.12 6.57) multivariate logistic regression analysis. high similar status. Educating prevent acquisition new minimizing disease manifestations HIV-Toxoplasma co-infected individuals important.