Genomic analyses of two Alteromonas stellipolaris strains reveal traits with potential biotechnological applications
作者： Marta Torres , Kar-Wai Hong , Teik-Min Chong , José Carlos Reina , Kok-Gan Chan
DOI: 10.1038/S41598-018-37720-2
关键词: Gene 、 Cloning 、 Genome 、 Enzyme 、 Biochemistry 、 Amidohydrolase 、 Strain (chemistry) 、 Fucose 、 Biology 、 Genomics
摘要: The Alteromonas stellipolaris strains PQQ-42 and PQQ-44, previously isolated from a fish hatchery, have been selected on the basis of their strong quorum quenching (QQ) activity, as well ability to reduce Vibrio-induced mortality coral Oculina patagonica. In this study, genome sequences both were determined analyzed in order identify mechanism responsible for QQ activity. Both PQQ-44 found degrade wide range N-acylhomoserine lactone (AHL) QS signals, possibly due presence an aac gene which encodes AHL amidohydrolase. addition, different colony morphologies exhibited by could be related differences observed genes encoding cell wall biosynthesis exopolysaccharide (EPS) production. strain produces more EPS (0.36 g l-1) than (0.15 g l-1), whose chemical compositions also differ. Remarkably, contains large amounts fucose, sugar used high-value biotechnological applications. Furthermore, contained non-ribosomal peptide synthase (NRPS) cluster with unknown genetic structure. synthesis enzymes other bioactive compounds identified, indicating that
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