Hippocampal Shape Analysis in Alzheimer's Disease and Frontotemporal Lobar Degeneration Subtypes
作者： Olof Lindberg , Mark Walterfang , Jeffrey C.L. Looi , Nikolai Malykhin , Per Östberg
关键词: Hippocampal formation 、 Dementia 、 Neuroscience 、 Progressive nonfluent aphasia 、 Pathology 、 Subiculum 、 Frontotemporal lobar degeneration 、 Semantic dementia 、 Frontotemporal dementia 、 Psychology 、 Atrophy
摘要: Hippocampal pathology is central to Alzheimer's disease (AD) and other forms of dementia such as frontotemporal lobar degeneration (FTLD). Autopsy studies have shown that certain hippocampal subfields are more vulnerable than others AD FTLD pathology, in particular the subiculum cornu ammonis 1 (CA1). We conducted shape analysis hippocampi segmented from structural T1 MRI images on clinically diagnosed patients controls. The subjects included 19 35 [13 (FTD), 13 semantic (SD), 9 progressive nonfluent aphasia (PNFA)] 21 Compared controls, SD displayed severe atrophy whole left hippocampus. PNFA FTD also side, restricted head FTD. Finally, most body with relative sparing head. Consistent neuropathological studies, atrophic deformation was found CA1 areas AD.
sci-hub.se 参考文章(48)
Marshal F. Folstein, Susan E. Folstein, Paul R. McHugh, “Mini-mental state” Journal of Psychiatric Research. ,vol. 12, pp. 189- 198 ,(1975) , 10.1016/0022-3956(75)90026-6
Jonathan H Morra, Zhuowen Tu, Liana G Apostolova, Amity E Green, Christina Avedissian, Sarah K Madsen, Neelroop Parikshak, Xue Hua, Arthur W Toga, Clifford R Jack Jr, Norbert Schuff, Michael W Weiner, Paul M Thompson, None, Automated 3D mapping of hippocampal atrophy and its clinical correlates in 400 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. Human Brain Mapping. ,vol. 30, pp. 2766- 2788 ,(2009) , 10.1002/HBM.20708
Kim S Graham, Jon S Simons, Katherine H Pratt, Karalyn Patterson, John R Hodges, Insights from semantic dementia on the relationship between episodic and semantic memory Neuropsychologia. ,vol. 38, pp. 313- 324 ,(2000) , 10.1016/S0028-3932(99)00073-1
D. Neary, J. S. Snowden, L. Gustafson, U. Passant, D. Stuss, S. Black, M. Freedman, A. Kertesz, P. H. Robert, M. Albert, K. Boone, B. L. Miller, J. Cummings, D. F. Benson, Frontotemporal lobar degeneration A consensus on clinical diagnostic criteria Neurology. ,vol. 51, pp. 1546- 1554 ,(1998) , 10.1212/WNL.51.6.1546
Alphonse Probst, Kirsten I. Taylor, Markus Tolnay, Hippocampal sclerosis dementia: a reappraisal Acta Neuropathologica. ,vol. 114, pp. 335- 345 ,(2007) , 10.1007/S00401-007-0262-1
Liana G Apostolova, Lisa Mosconi, Paul M Thompson, Amity E Green, Kristy S Hwang, Anthony Ramirez, Rachel Mistur, Wai H Tsui, Mony J de Leon, None, Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal Neurobiology of Aging. ,vol. 31, pp. 1077- 1088 ,(2010) , 10.1016/J.NEUROBIOLAGING.2008.08.008
Gil D Rabinovici, Bruce L Miller, None, Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs. ,vol. 24, pp. 375- 398 ,(2010) , 10.2165/11533100-000000000-00000
Eleanor A. Maguire, Catherine J. Mummery, Christian B�chel, Patterns of hippocampal-cortical interaction dissociate temporal lobe memory subsystems. Hippocampus. ,vol. 10, pp. 475- 482 ,(2000) , 10.1002/1098-1063(2000)10:4<475::AID-HIPO14>3.0.CO;2-X
Jeffrey Chee Leong Looi, Mark Walterfang, Martin Styner, Marc Niethammer, Leif Anders Svensson, Olof Lindberg, Per Östberg, Lisa Botes, Eva Örndahl, Phyllis Chua, Dennis Velakoulis, Lars-Olof Wahlund, Shape analysis of the neostriatum in subtypes of frontotemporal lobar degeneration : neuroanatomically significant regional morphologic change Psychiatry Research-neuroimaging. ,vol. 191, pp. 98- 111 ,(2011) , 10.1016/J.PSCYCHRESNS.2010.09.014
N.V. Malykhin, R.M. Lebel, N.J. Coupland, A.H. Wilman, R. Carter, In vivo quantification of hippocampal subfields using 4.7 T fast spin echo imaging. NeuroImage. ,vol. 49, pp. 1224- 1230 ,(2010) , 10.1016/J.NEUROIMAGE.2009.09.042