Signal Peptide Peptidase-Type Proteases: Versatile Regulators with Functions Ranging from Limited Proteolysis to Protein Degradation
作者： Sara Suna Yücel , Marius K. Lemberg
DOI: 10.1016/J.JMB.2020.05.014
关键词: Signal peptide peptidase 、 Chemistry 、 Endoplasmic reticulum 、 Regulated Intramembrane Proteolysis 、 Protein degradation 、 Enzyme 、 Proteases 、 Proteolysis 、 Biochemistry 、 Presenilin
摘要: … the translocation nascent peptide chain by signal peptidase cleavage. For the conserved signal peptide of human MHC-I molecules, the N-terminal signal peptide fragment is trimmed …
sci-hub.st 参考文章(132)
Sabrina Schrempf, Katja Kapp, Marius K. Lemberg, Bernhard Dobberstein, Post‑Targeting Functions of Signal Peptides Landes Bioscience. ,(2013)
Fumi Kano, Hisao Kondo, Akitsugu Yamamoto, Yayoi Kaneko, Keiji Uchiyama, Nobuko Hosokawa, Kazuhiro Nagata, Masayuki Murata, NSF/SNAPs and p97/p47/VCIP135 are sequentially required for cell cycle‐dependent reformation of the ER network Genes to Cells. ,vol. 10, pp. 989- 999 ,(2005) , 10.1111/J.1365-2443.2005.00894.X
Yu A. Chen, Richard H. Scheller, SNARE-mediated membrane fusion Nature Reviews Molecular Cell Biology. ,vol. 2, pp. 98- 106 ,(2001) , 10.1038/35052017
Regina Fluhrer, Gudula Grammer, Lars Israel, Margaret M. Condron, Christof Haffner, Elena Friedmann, Claudia Böhland, Axel Imhof, Bruno Martoglio, David B. Teplow, Christian Haass, A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b Nature Cell Biology. ,vol. 8, pp. 894- 896 ,(2006) , 10.1038/NCB1450
Bart De Strooper, Paul Saftig, Katleen Craessaerts, Hugo Vanderstichele, Gundula Guhde, Wim Annaert, Kurt Von Figura, Fred Van Leuven, Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein Nature. ,vol. 391, pp. 387- 390 ,(1998) , 10.1038/34910
Sarah A. Laurent, Franziska S. Hoffmann, Peer-Hendrik Kuhn, Qingyu Cheng, Yuanyuan Chu, Marc Schmidt-Supprian, Stefanie M. Hauck, Elisabeth Schuh, Markus Krumbholz, Heike Rübsamen, Johanna Wanngren, Mohsen Khademi, Tomas Olsson, Tobias Alexander, Falk Hiepe, Hans-Walter Pfister, Frank Weber, Dieter Jenne, Hartmut Wekerle, Reinhard Hohlfeld, Stefan F. Lichtenthaler, Edgar Meinl, γ-secretase directly sheds the survival receptor BCMA from plasma cells Nature Communications. ,vol. 6, pp. 7333- 7333 ,(2015) , 10.1038/NCOMMS8333
Bart De Strooper, Wim Annaert, Philippe Cupers, Paul Saftig, Katleen Craessaerts, Jeffrey S. Mumm, Eric H. Schroeter, Vincent Schrijvers, Michael S. Wolfe, William J. Ray, Alison Goate, Raphael Kopan, A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature. ,vol. 398, pp. 518- 522 ,(1999) , 10.1038/19083
Xiao-chen Bai, Chuangye Yan, Guanghui Yang, Peilong Lu, Dan Ma, Linfeng Sun, Rui Zhou, Sjors H. W. Scheres, Yigong Shi, An atomic structure of human γ-secretase Nature. ,vol. 525, pp. 212- 217 ,(2015) , 10.1038/NATURE14892
Jae Myoung Noh, Jihun Kim, Dae Yeon Cho, Doo Ho Choi, Won Park, Seung Jae Huh, Exome sequencing in a breast cancer family without BRCA mutation. Radiation oncology journal. ,vol. 33, pp. 149- 154 ,(2015) , 10.3857/ROJ.2015.33.2.149
F-F Hsu, C-T Yeh, Y-J Sun, M-T Chiang, W-M Lan, F-A Li, W-H Lee, L-Y Chau, Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity. Oncogene. ,vol. 34, pp. 2360- 2370 ,(2015) , 10.1038/ONC.2014.166