OPTICAL DETECTION OF SINGLE MOLECULES
作者： Shuming Nie , Richard N. Zare
DOI: 10.1146/ANNUREV.BIOPHYS.26.1.567
关键词: Instrumentation (computer programming) 、 Nanotechnology 、 Identification (biology) 、 Scientific disciplines 、 Chemistry 、 Nanostructured materials
摘要: Recent advances in ultrasensitive instrumentation have allowed for the detection, identification, and dynamic studies of single molecules condensed phase. This measurement capability provides a new set tools scientists to address important current problems explore frontiers many scientific disciplines, such as chemistry, molecular biology, medicine, nanostructured materials. review focuses on methodologies biological applications single-molecule detection based laser-induced fluorescence.
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