Influence of racing on the serum concentrations of acute-phase proteins and bone metabolism biomarkers in racing greyhounds.

摘要: Abstract This study was designed to evaluate the influence of racing on serum concentrations acute-phase proteins (APPs) C-reactive protein (CRP), haptoglobin (Hp) and amyloid A (SAA) in 32 endurance-racing greyhounds. The also aimed investigate effect a 7 km race bone biomarkers osteocalcin (OC), bone-specific alkaline phosphatase (b-ALP) pyridinoline cross-links (PYD). Total white blood cell (WBC) count, cortisol, tumour necrosis factor-α (TNF-α), vitamin D testosterone were determined. Blood samples collected 24 h prior (T0) within 2 h completion (T1). Compared baseline values, WBC count did not change significantly ( P  = 0.2300), Hp SAA increased, while TNF-α CRP decreased P  0.0001 for each). There no significant differences between pre- post-race OC PYD  = 0.9500  = 0.2600, respectively), but b-ALP increased  = 0.0004). Serum after  = 0.0100 0.0001, respectively). In this study, stimulated an response, demonstrated by increases Increased probably indicates metabolism deserves further study.