Recurrence from primary and secondary glomerulopathy after renal transplant

作者: Guillaume Canaud , Vincent Audard , Tomek Kofman , Philippe Lang , Christophe Legendre

DOI: 10.1111/J.1432-2277.2012.01483.X

关键词: Membranoproliferative glomerulonephritisKidney transplantationMembranous nephropathyFibrillary GlomerulonephritisInternal medicinePathologyNephrologyMedicineNephropathyTransplantationGlomerulonephritisGastroenterology

摘要: Glomerulonephritis is the primary cause of end-stage renal failure in 30-50% kidney transplant recipients and recurrence initial disease an important determinant long-term graft outcome after transplantation. Although transplantation remains best treatment option for patients with end stage diseases most cases, diagnosis management recurrences glomerulopathies are critical optimization improvement survival provide a unique opportunity to explore pathogenesis native disease. This review aims update knowledge large panel recurrent secondary glomerulonephritis transplantation, excluding diabetic nephropathy including focal segmental glomerulosclerosis, membranous nephropathy, IgA membranoproliferative glomerulonephritis, lupus, vasculitis but also less usual related sarcoidosis, AA AL amyloidosis, monoclonal immunoglobulin deposition disease, fibrillary glomerulonephritis.

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