Isosterism and bioisosterism in drug design.
作者： Alfred Burger
DOI: 10.1007/978-3-0348-7139-6_7
关键词: Elaboration 、 Drug 、 Working hypothesis 、 Molecular conformation 、 Computational biology 、 Computer science 、 Stereochemistry 、 Squalene monooxygenase 、 Isostere
摘要: In every scientific undertaking that is to break new ground, one has have a goal, working hypothesis, or leading idea fact. This will encourage research and help in the pursuit of worth-while objective, be it enrichment knowledge elaboration practical purpose. A medicinal scientist who hopes find biologically active drug guided by such considerations.
springer.com
springerlink.com参考文章(199)
Vincent du Vigneaud, Herbert McKennis, Sofia Simmonds, Karl Dittmer, George Bosworth Brown, THE INHIBITION OF THE GROWTH OF YEAST BY THIENYLALANINE Journal of Biological Chemistry. ,vol. 159, pp. 385- 394 ,(1945) , 10.1016/S0021-9258(19)52799-5
Alfred Burger, A Guide to the Chemical Basis of Drug Design ,(1983)
Yvonne Connolly Martin, Quantitative drug design: A critical introduction ,(1978)
Elmore Hathaway Northey, John Thomas Litchfield, Harold James White, The sulfonamides and allied compounds ,(1948)
William A. Carter, Selective Inhibitors Of Viral Functions ,(1973)
D.J. Triggle, C.R. Triggle, Chemical pharmacology of the synapse ,(1976)
Andrejus Korolkovas, Essentials of molecular pharmacology : background for drug design Wiley-Interscience. ,(1970)
Glenn A. Brewer, Klaus Florey, Control Section, Analytical profiles of drug substances Academic Press. ,(1972)
Corwin Herman Hansch, Albert Leo, Substituent constants for correlation analysis in chemistry and biology Published in <b>1979</b> in New York NY) by Wiley. ,(1979)
Lothar Birckenbach, Karl Huttner, Über die Cyan-Abkömmlinge der flüchtigen Hydride Zeitschrift für anorganische und allgemeine Chemie. ,vol. 190, pp. 1- 26 ,(1930) , 10.1002/ZAAC.19301900102