Genomic landscape of CDK12 mutated metastatic castrate-resistant prostate cancer (mCRPC).
作者： Petros Grivas , Gennady Bratslavsky , Joseph M Jacob , Andrea Necchi , Philippe E Spiess
DOI: 10.1200/JCO.2021.39.6_SUPPL.165
关键词: CDK12 、 Castrate-resistant prostate cancer 、 Prostate cancer 、 Cancer research 、 Immune checkpoint inhibitors 、 Medicine 、 Unmet needs
摘要: 165Background: Identifying prostate cancer patients likely to benefit from immune checkpoint inhibitors (ICPI) remains an unmet need. Specific loss-of-function genomic alterations (GA) in CDK12 are...
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