The influence of glucose concentration on citric acid production and morphology of Aspergillus niger in batch and culture

摘要: Studies in conventional batch culture confirmed that initial glucose concentration the fermentation medium affected both rate of citric acid by Aspergillus niger and morphology producer micro-organism. A series fed-batch (glucostat) experiments, which was kept constant whereas all other conditions were allowed to change, used eliminate effects decreasing sugar found during experiments. The level had a marked effect on production rates; specific formation increased with increasing (batch culture) or levels (glucostat culture), methods, growth for first 48 h fermentation. reduction observed mean length filaments at low could be explained branching frequency as result early stages size mycelial clumps reduced their shape also ratio between perimeter clump its core decreased. Very glucostat striking metabolism micro-organism because decreased favor changed doubling pellet formation. main morphological observations cultures seemed related rate, is restricted concentration, and, thus, indirectly media. shown lead significant noncatalysed entry into mycelium, accounted productivity changes.