A hydrophobic organelle probe based on aggregation-induced emission: Nanosuspension preparation and direct use for endoplasmic reticulum imaging in living cells.
作者： Sichao Zheng , Cuihong Huang , Xuyan Zhao , Yong Zhang , Shuwen Liu
DOI: 10.1016/J.SAA.2017.08.016
关键词: Endoplasmic reticulum 、 Chemistry 、 Molecular imaging 、 Biocompatibility 、 Nanotechnology 、 Organelle 、 Aqueous solution 、 Nanoparticle 、 Fluorescence 、 Biophysics 、 Dynamic light scattering
摘要: Organic fluorophores have a wide range of biological uses and are usually needed to be prepared as water-soluble compounds or nanoparticles for applications in aqueous biosystems owing to their hydrophobic properties, which often is a complex, time-consuming and high-cost process. Here, the nanoparticle preparation of hydrophobic fluorophores and their application in cell imaging have been investigated. It was found: a) fetal bovine serum (FBS) shows an excellent dispersion effect on hydrophobic small-molecule organic …
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