Gene panel for the prognosis of prostate cancer

作者: Nadège Rabiau , Christophe Haug , Yves-Jean Bignon , Yann Dantal , Dominique Bernard-Gallon

DOI:

关键词: Prostate cancerGene panelOncologyMUC1GSTP1Cancer researchMedicinePCA3Internal medicine

摘要: The present invention relates to a microfluidic plate for the diagnosis and/or prognosis of prostate cancer, as well method cancer in accordance with use such plate. Specifically, can be used analyzing expression level genes BRCA1, BRCA2, AR, IGF1, EPHB2, AMACR, ESR1, ESR2, BCL2, RNASEL, MUC1, IL18, COL4A3, GSTP1 and RASSF1 by RT-qPCR.

参考文章(11)
Weiliang Qiu, Brian Liu, Joshua Ehrlich, Tumor associated markers in the diagnosis of prostate cancer ,(2007)
Steven Eschrich, Javier F. Torres-Roca, Gene signature for the prediction of radiation therapy response ,(2008)
Jack A. Schalken, Sander Adriaan Jannink, Daphne Hessels, Franciscus Petrus Smit, Molecular markers in prostate cancer ,(2009)
David Abia, Ortiz Angel Ramirez, Alonso Carlos Matinez, Vives Elisabet Rosell, Gascon Raquel Bermudo, Okatsu Timothy Thomson, Gueerri Elias Campo, Ruiz Luis Pedro Fernandez, Fabrega Berta Ferrer, Method for the molecular diagnosis of prostate cancer and kit for implementing same ,(2007)
Mark A. Rubin, Francesca Demichelis, Biomarkers for predicting prostate cancer progression ,(2006)
Thorsten Schlomm, Esther Näkel, Andreas Lübke, Andreas Buness, Felix K.-H. Chun, Thomas Steuber, Markus Graefen, Ronald Simon, Guido Sauter, Annemarie Poustka, Hartwig Huland, Andreas Erbersdobler, Holger Sültmann, Olaf J.C. Hellwinkel, Marked Gene Transcript Level Alterations Occur Early During Radical Prostatectomy European Urology. ,vol. 53, pp. 333- 346 ,(2008) , 10.1016/J.EURURO.2007.03.075
David I. Quinn, Susan M. Henshall, Robert L. Sutherland, Molecular markers of prostate cancer outcome European Journal of Cancer. ,vol. 41, pp. 858- 887 ,(2005) , 10.1016/J.EJCA.2004.12.035
Arul M. Chinnaiyan, Mark A. Rubin, Arun Sreekumar, Expression profile of prostate cancer ,(2002)
Mark A. Reynolds, Kumar Kastury, Jack Groskopf, Jack A. Schalken, Harry Rittenhouse, Molecular markers for prostate cancer. Cancer Letters. ,vol. 249, pp. 5- 13 ,(2007) , 10.1016/J.CANLET.2006.12.029
Danute M. Bankaitis-Davis, Lisa Siconolfi, Kathleen Storm, Karl Wassmann, Gene Expression Profiling for Identification, Monitoring and Treatment of Prostate Cancer ,(2007)