Differential Correlation of Serum BDNF and microRNA Content in Rats with Rapid or Late Onset of Heavy Alcohol Use

作者: Yann Ehinger , Khanhky Phamluong , David Darevesky , Melanie Welman , Jeffrey J. Moffat

DOI: 10.1101/2019.12.18.881680

关键词: EndocrinologyPrefrontal cortexCirculating MicroRNAInternal medicineMedicineDownregulation and upregulationLate onsetPlateletNeurotrophic factorsAlcoholAlcohol abuse

摘要: Heavy alcohol use reduces the levels of the brain‐derived neurotrophic factor (BDNF) in the prefrontal cortex of rodents through the upregulation of microRNAs (miRs) targeting BDNF …

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