Functional Outcome after Language Mapping for Glioma Resection

作者: Nader Sanai , Zaman Mirzadeh , Mitchel S. Berger

DOI: 10.1056/NEJMOA067819

关键词: MedicineLanguage functionGliomaSurgeryCortical stimulation mappingDyslexiaLanguage mappingCortex (anatomy)ResectionCentral nervous system disease

摘要: Background Language sites in the cortex of brain vary among patients. mapping while patient is awake an intraoperative technique designed to minimize language deficits associated with brain-tumor resection. Methods To study function after resection mapping, we examined 250 consecutive patients gliomas. Positive (i.e., regions brain, 1 cm by cm, which were temporarily inactivated means a bipolar electrode) identified and categorized into cortical maps. The tumors resected up from areas where stimulation produced disturbance language. Our strategy did not require identification stimulation-induced within field exposure. Results A total 145 (58.0%) had at least one site speech arrest, 82 anomia, 23 alexia....

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