Treatment of chancroid in resource-poor countries

摘要: Chancroid, formerly a major cause of the genital ulcer disease syndrome, remains an important cofactor in both transmission and acquisition HIV-1 infection. Those countries with greatest burden HIV also have some highest prevalence rates chancroid worldwide. The diagnosis chancroid, caused by fastidious bacterium Haemophilus ducreyi, is expensive difficult many resource-poor areas. These areas world use syndromic management to treat ulcers such approach has proven effective reducing bacterial diseases. There are currently inexpensive single-dose therapies available chancroid. Single-dose regimens, given at first presentation, improve compliance reduce risk sexually transmitted infections. Bacterial resistance several antimicrobial agents increased over years continued threat therapy. Follow-up cases, partner notification and...