Expression of CD64 on neutrophils can be used to predict the severity of bloodstream infection before broad range 16S rRNA PCR

摘要: The aging population and increased incidence of severe bacterial infection can lead to sepsis. Interest early identification endangered patients pathogen do not always confirm the infection. To use biomarkers help in opportunity start therapy timeously. All were defined 33 out 96 patients. Thirty-two (97 %) had 1 (3 patient systemic inflammatory response syndrome (SIRS) without PCR confirmed 27 cases blood cultures 8. Area under curve (AUC) for CD64 was 1.00, meanwhile other showed 2-fold smaller AUC positive index associated with (p < 0.001) could be used assessment SIRS severity = 0.037). As regards our results, limited only patients, served as a good parameter predict determine severity. broad range 16S ribosomal RNA (rRNA) proved an excellent tool bloodstream highest AUC, which exceeded all others, outcome rRNA from whole blood. However, C-reactive protein (CRP), procalcitonin (PCT) sCD14 are much easier faster measure, but values elevated clinical assessments.