Rituximab and dose dense chemotherapy in primary breast lymphoma

作者: Agustin Avilés , Claudia Castañeda , Natividad Neri , Sergio Cleto , M Jesús Nambo

DOI: 10.3324/HAEMATOL.10892

关键词: Dose-dense chemotherapySurgeryRegimenOncologyStage (cooking)Female patientComplete responsePrimary Breast LymphomaToxicityInternal medicineRituximabMedicine

摘要: Treatment of primary breast lymphoma (PBL) remains unsatisfactory. We assess a clinical study to evaluate efficacy and toxicity dose dense regimen (CEOP-14) rituximab in 32 previously untreated female patients with PBL early stage. There was no difference complete response rate (87%), event free-survival (75%) overall survival (63%) compared historical patients.

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