作者: Philip M. Sass , Luigi Grasso , Eric Routhier , Nicholas C. Nicolaides , Qimin Chao
DOI:
关键词: Autoimmune disease 、 Antigen 、 Biology 、 Virology 、 Immunology 、 Epitope 、 Biological activity 、 Infectious disease (medical specialty) 、 Antibody 、 Primary and secondary antibodies 、 Monoclonal antibody
摘要: Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, methods of generating the hybridoma are provided. Target antigens epitopes also The may be used in therapeutic methods, for example treatment cancer, infectious disease, or autoimmune disease.