Antigenic GM-CSF peptides and antibodies to GM-CSF

作者: Philip M. Sass , Luigi Grasso , Eric Routhier , Nicholas C. Nicolaides , Qimin Chao

DOI:

关键词: Autoimmune diseaseAntigenBiologyVirologyImmunologyEpitopeBiological activityInfectious disease (medical specialty)AntibodyPrimary and secondary antibodiesMonoclonal antibody

摘要: Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, methods of generating the hybridoma are provided. Target antigens epitopes also The may be used in therapeutic methods, for example treatment cancer, infectious disease, or autoimmune disease.

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